BCAN is committed to supporting bladder cancer research. From its inception, BCAN has cultivated a strong partnership with the leading members of the bladder cancer medical community to encourage collaboration among all the parties dedicated to the study of bladder cancer and its prevention, diagnosis and treatment. Starting in 2010, BCAN provided $25,000 one-year grants to support young investigators conducting bladder cancer research. In 2011 BCAN received a generous multi-year gift from Raymond and Maria Floyd, for the Raymond and Maria Floyd Award for Bladder Cancer Research in 2011 and 2012. BCAN’s current research priorities are guided by the Bladder Cancer Research Network (BRCN) Management Committee. Our goal is to identify the best and most promising research that will provide the greatest opportunity to advance the understanding of bladder cancer and how to improve management and treatment of this disease. BCAN raises funds and awards grants to support innovative bladder cancer research to develop lifesaving treatments.
Information about applying for awards in 2015 should be available in January 2015 for the Young Investigator Awards and Bladder Cancer Research Innovation Award, and in March 2015 for the John Quale Travel Fellowship Program. Please contact BCAN if you have any questions at firstname.lastname@example.org.
A new award for 2014, BCAN announces the Bladder Cancer Research Innovation Award of $300,000 over a two-year period for an experienced investigator who will break new ground in the field of bladder cancer. The aim of the award is to support exceptionally novel and creative projects with great potential to produce breakthroughs in the management of bladder cancer. For more information about this award, please click here.
2014 Bladder Cancer Research Innovation Award Winner
William Kim, MD
Associate Professor of Medicine, Urology, and Genetics
University of North Carolina at Chapel Hill and UNC Lineberger Comprehensive Cancer Center
“Immune Characterization of High-Grade Bladder Cancer.”
Click here to view press release
Raising the bar on research, BCAN launched its Young Investigator Awards in 2013, comprised of three research awards of $100,000 each, over a two-year period. These grants will fund researchers who may be working in basic, translational, clinical, epidemiologic, bioengineering or any other scientific or research field, but are also working in a research environment capable of supporting transformational bladder cancer research. BCAN would like to recognize the generosity of The JPB Foundation for under-writing two of the 2014 Young Investigator Awards. The New York based philanthropy works to enhance the quality of life in the United States through transformational initiatives that promote the health of our communities by creating opportunities for those in poverty, promoting pioneering medical research, and enriching and sustaining our environment. The program was seeded through a $250,000 challenge grant received from the Gerald C. McNamara and Renée K. Petrofes Charitable Fund. BCAN responded by raising more than $500,000 in additional private funds to further develop the program. For more information about this award, please click here. View Press Release
2014 Young Investigator Award Winners
BCAN YOUNG INVESTIGATOR AWARD
Sunny Guin, PhD, Postdoctoral Fellow, University of Colorado at Denver, for his project “The Role, Relationship and Therapeutic Potential of HAS2 and AGL in Bladder Cancer.” Dr. Guin will be investigating a novel signaling pathway and potential drug-able target for bladder cancer tumor formation, aggressiveness, and metastasis.
JPB FOUNDATION YOUNG INVESTIGATOR AWARD
Ryoichi Saito, MD, PhD, Research Associate, University of North Carolina at Chapel Hill, for his project, “Consequences of ARID1A Inactivation in Bladder Cancer.” Dr. Saito will be expanding the findings from The Cancer Genome Atlas Project in bladder cancer, specifically focusing on a mutated gene in one of the most frequently altered pathways to better characterize its mechanism in tumor development. He will also be developing a novel mouse model for bladder cancer.
JPB FOUNDATION YOUNG INVESTIGATOR AWARD
Dmitriy Zamarin, MD, PhD Hematology/Oncology Fellow, Memorial Sloan-Kettering Cancer Center, for his project “Defining Immunotherapy Targets in Bladder Cancer Microenvironment Using Oncolytic Viruses.” Dr. Zamarin is examining using an oncolytic virus to activate the immune system to recognize cancer cells, and combined with other immunotherapies to combat metastatic bladder cancer. Dr. Zamarin will also work on identifying immune resistance mechanisms in bladder cancer.
2013 Young Investigator Award Winners
BCAN YOUNG INVESTIGATOR AWARD
David DeGraff, Ph.D., Postdoctoral Fellow, Vanderbilt University Medical Center. Project Title: Transcriptional Control of Bladder Cancer Tumorigenesis. The award will help support Dr. DeGraff’s research to investigate gene expression of two transcription factors which regulate cell behavior: FOXA1 and AP2 gamma, and their role in bladder cancer risk.
JAMES FAMILY YOUNG INVESTIGATOR AWARD
Gopa Iyer, MD, Clinical Instructor, Memorial Sloan-Kettering Cancer Center. Project Title: Identifying Predictors of Response to mTOR-targeted Therapies in Bladder Cancer. The award will support Dr. Iyer’s research to examine the role of the Tuberous Sclerosis 1 (TSC1) gene in bladder cancer tumors and improve understanding of the genetic alterations in bladder cancer to identify patients who will most likely benefit from targeted therapies in this disease.
RAYMOND AND MARIA FLOYD FAMILY YOUNG INVESTIGATOR AWARD
Debashis Sahoo, PhD, Instructor, Stanford University. Project Title: High resolution molecular analysis of CD47-mediated immune escape in bladder cancer. The award will support Dr. Sahoo’s research to investigate interactions between the immune system and bladder cancer specifically looking at CD47 variants.
Started in 2009, the John Quale Travel Fellowship Program provides $1700 awards to defray travel-related costs for early career investigators interested in bladder cancer research to attend the annual Bladder Cancer Think Tank Meeting, a unique opportunity to meet and learn from leaders in the field. The primary mission of this meeting is to enhance collaboration among physicians and researchers who are dedicated to the prevention, diagnosis, and treatment of bladder cancer. The Travel Fellowship Program seeks to engage more early-career individuals with interests related to bladder cancer including basic scientists, urologists, oncologists, and pathologists. For more information about this program please click here.
2014 John Quale Travel Fellows
Philip Ho, MD, Urologic Oncology Fellow, University of Texas M.D. Anderson Cancer Center
Research abstract: “Stat3 Transgenic Mice as a Model for Human Basal Subtype of Invasive Bladder Cancer”
Tim Lautenschlaeger, MD , Research Assistant Professor, Senior Radiation Oncology Resident, The Ohio State University
Research abstract: “Novel Predictive Micro-RNA Signature in the Setting of Selective Trimodality Bladder Preservation Therapy”
Young Lee, PhD, Postdoctoral Fellow, National Cancer Institute, Urologic Oncology Branch
Research abstract: “Characterization of Met Signaling in Urothelial Carcinoma of the Bladder”
Anirban Mitra, MD, PhD, Senior Research Associate, Department of Pathology and Laboratory Medicine / Center for Personalized Medicine, University of Southern California
Research abstract: “Discovery and Validation of Prognostic Genomic-Based Signatures in High-Risk Bladder Cancer Following Cystectomy”